Comparison of personality and psychopathology in patients with Fabry disease and patients with end-stage renal disease: a preliminary study

Comparison of personality and psychopathology in patients with Fabry disease and patients with end-stage renal disease: a preliminary study

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BackgroundThe present study aimed to investigate personality characteristics and psychopathological symptoms in patients with Fabry disease (FD) vs a group of individuals with end-stage renal disease (ESRD).MethodsA total of 36 patients, equally divided into patients with FD and patients with ESRD (control group), were administered the following tools: the Millon Clinical Multiaxial Inventory III (MCMI-III) to evaluate personality psychopathology and the Symptom Checklist-90-R cupless bra pattern (SCL-90-R) to assess symptoms of psychopathology.ResultsSignificantly higher levels of Schizoid, Depressive, and Negativistic personality traits emerged in FD patients.

Moreover, statistically significant differences in Anxiety, Interpersonal Sensitivity, Obsessive-Compulsive, Depression, Somatization, and Psychoticism dimensions of the SCL-90-R were found, with higher levels of each dimension in patients with FD than ESRD.ConclusionsThe literature, albeit limited, highlights how patients with FD are at higher risk of developing psychological distress and psychopathology than patients presenting other chronic diseases such as ESRD.Using psychological therapies together with princess jasmine silhouette standard treatments for FD can promote condition acceptance, reduce emotional burden, and relieve psychopathological symptoms in FD patients.